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Stage 2 contains perna canaliculus, glucosamine HC1, DMG (dimethylglycine), MSM (methylsulfonylmethane), and manganese for added joint support. MSM also provides added comfort during recovery. This formula is designed specifically for moderate stages of joint dysfunction. GlycoFlex 2 - Rebuild For use in dogs only. Comprehensive support for connective tissue health For adult and mature dogs as well as sporting, hunting, and working breeds Helps rebuild normal joint function as part of follow-up to orthopedic surgery For dogs with moderate joint dysfunction DMG is used to support proper immune response, cardiovascular and skin health. It can also help reduce stress and has anti-inflammatory properties. 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