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SAMe contributes to better pet health through chemical processes including: transmethylation, transsulfuration, and aminopropylation which can affect the liver, joint, and mood health in animals. Liver Health SAMe improves phospholipids production during the process of transmethylation, which promotes better bile flow through the liver\'s cell membranes. Through a process called transsulfuration, SAMe is converted into glutathione, a potent antioxidant and liver detoxifier. The liver can acquire from methionine in common pet foods, however your pet\'s body may not process enough SAMe on its own due to old age, insufficient diet, or other inhibiting reasons. Using NutraLife Pet\'s SAMe will help this imbalance. Joint Health SAMe plays a critical role to produce methylthioadenosine (MTA) during the called aminopropylation. MTA supports cartilage matrix production in joints, and may help maintain the effectiveness of proteoglycans. Proteoglycans are molecules that are critical for lubricating joints. SAMe and Overall Well-Being It has been reported that animals on a SAMe regimen have gained improved appetite, activity and attitude. NutraLife Pet SAMe 400mg (30 tablets) Exogenous form of S-Adenosyl-Methionine Time-Proven form of SAMe Joint and Liver Supplement Pharmaceutical Grade For all classes of large dogs More Info Arthritis and Joint Supplements Find more joint supplements. Pet Arthritis Pet arthritis guide for dogs & cats Alternative Joint Supplements Find more solutions for proper pet nutrition. Importance of Nutrition Learn how to maintain a healthy meal plan for your pet. 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