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Designed to work with the ThunderEase Dog Calming Diffuser, this handy refill helps put an end to problem barking, destructive chewing, trembling and other anxious behaviors by mimicking a mother\'s natural nursing pheromones. Reduce anxiety and help your pup feel safe and less-stressed without all the unwanted side-effects of sedatives or antidepressants. Tested to be over 90% effective for reducing stress, this is the perfect way to soothe new, anxious and aggressive pets while preventing unwanted or destructive behaviors. Key Benefits: Drug-Free formula eases your pet\'s stress without unwanted side-effects such as sedation. Continuously releases calming pheromones for up to 30 days, so your pet can feel calm for longer. For best results use for the full 30 days. Helps soothe travel anxiety experienced during airline travel, car rides and moving. Relaxes pets during stressful environments and events such as visiting the vet, anxiety while boarding or kenneling and remodeling. Eases symptoms of stress and anxiety such as problem barking, destructive behavior, inappropriate chewing and peeing. 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