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Stage 3 contains perna canaliculus, glucosamine HCl, DMG (dimethylglycine), MSM (methylsulfonylmethane), manganese, vitamin C, vitamin E, selenium, grape seed extract, and gutathione. GlycoFlex® 3 helps alleviate severe discomfort and joint stiffness, and is the best choice for maximum support for joint dysfunction. GlycoFlex 3 – Restore For use in dogs only. For geriatric, retired, working, and sporting breeds Can be used in conjunction with NSAIDS Provides maximum support for dogs with advanced stages of joint dysfunction DMG is used to support proper immune response, cardiovascular and skin health. It can also help reduce stress and has anti-inflammatory properties. 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